Utrophin up-regulation by an artificial transcription factor in transgenic mice

Utrophin up-regulation by an artificial transcription factor in transgenic mice

Duchenne Muscular Dystrophy (DMD) is a severe muscle degenerative disease, due to absence of dystrophin. There is currently no effective treatment for DMD. Our aim is to up-regulate the expression level of the dystrophin related gene utrophin in DMD, complementing in this way the lack of dystrophin...

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Bibliographic Details
Main Authors:	Mattei, E, Corbi, N, Di Certo, MG, Strimpakos, G, Severini, C, Onori, A, Desantis, A, Libri, V, Buontempo, S, Floridi, A, Fanciulli, M, Baban, D, Davies, K, Passananti, C
Format:	Journal article
Language:	English
Published:	Public Library of Science 2007

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