The pharmacological and anatomical substrates of the amphetamine response in the rat.
Bilateral 6-hydroxydopamine microinjections into the substantia nigra abolished both the locomotor and stereotyped responses to d-amphetamine in adult rats. The lesions resulted in a depletion of over 99 per cent of striatal tyrosine hydroxylase activity (indicating a near total lesion of the nigro...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1975
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