The pharmacological and anatomical substrates of the amphetamine response in the rat.

Bilateral 6-hydroxydopamine microinjections into the substantia nigra abolished both the locomotor and stereotyped responses to d-amphetamine in adult rats. The lesions resulted in a depletion of over 99 per cent of striatal tyrosine hydroxylase activity (indicating a near total lesion of the nigro...

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Main Authors: Creese, I, Iversen, S
格式: Journal article
语言:English
出版: 1975