| الملخص: | <p><strong>Chapter I</strong> describes the concept of chirality and enantioselective synthesis. Organocatalysis is then introduced, with a focus on bifunctional organocatalysis and superbases in asymmetric methodology. Finally, bifunctional iminophosphorane catalysis is introduced and discussed.</p>
<p><strong>Chapter II</strong> describes the development of the first organocatalytic conjugate addition to unactivated α,β-unsaturated amides, exemplified by a highly enantioselective sulfa-Michael addition, and along with that the development of 3rd generation BIMP catalysts.</p>
<p><strong>Chapter III</strong> describes the development of the direct catalytic enantioselective conjugate addition of nitroalkanes to unactivated α,β-unsaturated esters, and the enantioselective synthesis of a range of APIs.</p>
<p><strong>Chapter IV</strong> discusses the NMR-aided pKBH+ measurements used to determine the basicity of iminophosphoranes. Furthermore, it describes a newly developed, analogous, but more rapid method for the determination of pKBH+ values, as well as the synthesis of a highly basic iminophosphorane.</p>
<p><strong>Chapter V</strong> contains the references for previous chapters. <strong>Chapter VI</strong> and <strong>Chapter VII</strong> contain the experimental details and analytical data of procedures and products described in <strong>Chapter II</strong> and <strong>Chapter III</strong>, and the <strong>Appendix</strong> contains synthetic information related to Chapter IV.</p>
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