Commentary. A picture of Mitf in melanoma immortality.
The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senesce...
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| Format: | Journal article |
| Language: | English |
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2011
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