Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.

Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.

The presence of multiple (5-100) colorectal adenomas suggests an inherited predisposition, but the genetic aetiology of this phenotype is undetermined if patients test negative for Mendelian polyposis syndromes such as familial adenomatous polyposis (FAP) and MUTYH-associated polyposis (MAP). We inv...

Podrobná bibliografie
Hlavní autoři:	Cheng, T, Gorman, M, Martin, L, Barclay, E, Casey, G, Saunders, B, Thomas, H, Clark, S, Tomlinson, I
Médium:	Journal article
Jazyk:	English
Vydáno:	2014

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