Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue.
This article presents the first evidence that the DNA base analogue 1,3-diaza-2-oxophenoxazine, tC(O), is highly fluorescent, both as free nucleoside and incorporated in an arbitrary DNA structure. tC(O) is thoroughly characterized with respect to its photophysical properties and structural performa...
Main Authors: | Sandin, P, Börjesson, K, Li, H, Mårtensson, J, Brown, T, Wilhelmsson, L, Albinsson, B |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2008
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Lignende værker
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Fluorescent properties of DNA base analogue tC upon incorporation into DNA--negligible influence of neighbouring bases on fluorescence quantum yield.
af: Sandin, P, et al.
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DNA adopts normal B-form upon incorporation of highly fluorescent DNA base analogue tC: NMR structure and UV-Vis spectroscopy characterization.
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Quadracyclic adenine: a non-perturbing fluorescent adenine analogue.
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Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue
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Synthesis and oligonucleotide incorporation of fluorescent cytosine analogue tC: a promising nucleic acid probe.
af: Sandin, P, et al.
Udgivet: (2007)