Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including 34,840 cases and 114,981 controls, overwhelmingly of European descent. We identified ten previously unreported T2D susceptib...

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Podrobná bibliografie
Hlavní autoři:	Morris, A, Voight, B, Teslovich, T, Ferreira, T, Segrè, A, Steinthorsdottir, V, Strawbridge, R, Khan, H, Grallert, H, Mahajan, A, Prokopenko, I, Kang, H, Dina, C, Esko, T, Fraser, R, Kanoni, S, Kumar, A, Lagou, V, Langenberg, C, Luan, J, Lindgren, C, Müller-Nurasyid, M, Pechlivanis, S, Rayner, N, Scott, L
Médium:	Journal article
Jazyk:	English
Vydáno:	2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Autor Morris, A, Voight, B, Teslovich, T, Ferreira, T, Segrè, A, Steinthorsdottir, V, Strawbridge, R, Khan, H, Grallert, H, Mahajan, A, Prokopenko, I, Kang, H, Dina, C, Esko, T, Fraser, R, Kanoni, S, Kumar, A, Lagou, V, Langenberg, C, Luan, J, Lindgren, C, Müller-Nurasyid, M, Pechlivanis, S, Rayner, N, Scott, L

Vydáno 2012

Journal article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Autor Morris, A, Voight, B, Teslovich, T, Ferreira, T, Segrè, A, Steinthorsdottir, V, Strawbridge, R, Khan, H, Grallert, H, Mahajan, A, Prokopenko, I, Kang, H, Dina, C, Esko, T, Fraser, R, Kanoni, S, Kumar, A, Lagou, V, Langenberg, C, Luan, J, Lindgren, C, Müller-Nurasyid, M, Pechlivanis, S, Rayner, N, Scott, L

Vydáno 2012

Journal article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

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