Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including 34,840 cases and 114,981 controls, overwhelmingly of European descent. We identified ten previously unreported T2D susceptib...

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Detalhes bibliográficos
Principais autores: Morris, A, Voight, B, Teslovich, T, Ferreira, T, Segrè, A, Steinthorsdottir, V, Strawbridge, R, Khan, H, Grallert, H, Mahajan, A, Prokopenko, I, Kang, H, Dina, C, Esko, T, Fraser, R, Kanoni, S, Kumar, A, Lagou, V, Langenberg, C, Luan, J, Lindgren, C, Müller-Nurasyid, M, Pechlivanis, S, Rayner, N, Scott, L
Formato: Journal article
Idioma:English
Publicado em: 2012