The role of developmental stage specific programmes in infant acute lymphoblastic leukaemia

<p>The MLL rearrangement which causes the poor prognosis of infant acute lymphoblastic leukemia (iALL) occurs before birth. Fetal haematopoietic stem and progenitor cells (HSPC) have different gene expression profiles to their postnatal counterparts. One such fetal specific oncogene, LIN28B is...

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书目详细资料
主要作者: Ling, R
其他作者: Roy, A
格式: Thesis
语言:English
出版: 2024
主题: