Drosophila Syncrip binds the gurken mRNA localisation signal and regulates localised transcripts during axis specification.
In the Drosophila oocyte, mRNA transport and localised translation play a fundamental role in axis determination and germline formation of the future embryo. gurken mRNA encodes a secreted TGF-α signal that specifies dorsal structures, and is localised to the dorso-anterior corner of the oocyte via...
Main Authors: | McDermott, S, Meignin, C, Rappsilber, J, Davis, I |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2012
|
Similar Items
-
Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
by: Halstead, J
Published: (2013) -
Elucidating the molecular mechanism that determines the specific localisation of gurken mRNA during Drosophila development
by: Gill, K
Published: (2017) -
Localised translation of gurken/TGF-α mRNA during axis specification is controlled by access to Orb/CPEB on Processing bodies
by: Davidson, A, et al.
Published: (2016) -
UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila.
by: Meignin, C, et al.
Published: (2008) -
Evidence for a transport-trap mode of Drosophila melanogaster gurken mRNA localization.
by: Lan Lan, et al.
Published: (2010-11-01)