Drosophila Syncrip binds the gurken mRNA localisation signal and regulates localised transcripts during axis specification.
In the Drosophila oocyte, mRNA transport and localised translation play a fundamental role in axis determination and germline formation of the future embryo. gurken mRNA encodes a secreted TGF-α signal that specifies dorsal structures, and is localised to the dorso-anterior corner of the oocyte via...
Váldodahkkit: | McDermott, S, Meignin, C, Rappsilber, J, Davis, I |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2012
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Geahča maid
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Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
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Localised translation of gurken/TGF-α mRNA during axis specification is controlled by access to Orb/CPEB on Processing bodies
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