Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population.

Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population.

Hepatocyte nuclear factor (HNF)-4alpha is part of a transcription factor network that is key for the development and function of the beta-cell. Rare mutations in the HNF4alpha gene cause maturity-onset diabetes of the young. A number of type 2 diabetes linkage studies have found evidence of linkage...

Полное описание

Библиографические подробности
Главные авторы:	Weedon, M, Owen, K, Shields, B, Hitman, G, Walker, M, McCarthy, M, Love-Gregory, L, Permutt, M, Hattersley, A, Frayling, T
Формат:	Journal article
Язык:	English
Опубликовано:	2004

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