Decapping is preceded by 3' uridylation in a novel pathway of bulk mRNA turnover.
Both end structures of eukaryotic mRNAs, namely the 5' cap and 3' poly(A) tail, are necessary for transcript stability, and loss of either is sufficient to stimulate decay. mRNA turnover is classically thought to be initiated by deadenylation, as has been particularly well described in Sac...
Główni autorzy: | Rissland, O, Norbury, C |
---|---|
Format: | Journal article |
Język: | English |
Wydane: |
2009
|
Podobne zapisy
-
Eukaryotic mRNA Decapping Activation
od: Elva Vidya, i wsp.
Wydane: (2022-03-01) -
RNA decay via 3' uridylation.
od: Scott, D, i wsp.
Wydane: (2013) -
3' Uridylation and the regulation of RNA function in the cytoplasm.
od: Norbury, C
Wydane: (2010) -
Uridylation regulates mRNA decay directionality in fission yeast
od: Maciej Grochowski, i wsp.
Wydane: (2024-09-01) -
Uridylation and PABP Cooperate to Repair mRNA Deadenylated Ends in Arabidopsis
od: Hélène Zuber, i wsp.
Wydane: (2016-03-01)