Inflammatory gene expression associates with hepatitis B virus cccDNA- but not integrant-derived transcripts in HBeAg negative disease

Chronic hepatitis B virus (HBV) infection is a global health problem that presents as a spectrum of liver disease, reflecting an interplay between the virus and the host immune system. HBV genomes exist as episomal covalently closed circular DNA (cccDNA) or chromosomal integrants. The relative contr...

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Bibliographic Details
Main Authors: Magri, A, Harris, JM, D'Arienzo, V, Minisini, R, Jühling, F, Wing, PAC, Rapetti, R, Leutner, M, Testoni, B, Baumert, TF, Zoulim, F, Balfe, P, Pirisi, M, McKeating, JA
Format: Journal article
Language:English
Published: MDPI 2022