tidal ventilation model for oxygenation in respiratory failure
We develop tidal-ventilation pulmonary gas-exchange equations that allow pulmonary shunt to have different values during expiration and inspiration, in accordance with lung collapse and recruitment during lung dysfunction [Am. J. Respir. Crit. Care Med. 158 (1998) 1636]. Their solutions are tested a...
| Príomhchruthaitheoirí: | , , , |
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| Formáid: | Journal article |
| Foilsithe / Cruthaithe: |
2003
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| Achoimre: | We develop tidal-ventilation pulmonary gas-exchange equations that allow pulmonary shunt to have different values during expiration and inspiration, in accordance with lung collapse and recruitment during lung dysfunction [Am. J. Respir. Crit. Care Med. 158 (1998) 1636]. Their solutions are tested against published animal data from intravascular oxygen tension and saturation sensors. These equations provide one explanation for (i) observed physiological phenomena, such as within-breath fluctuations in arterial oxygen saturation and blood-gas tension; and (ii) conventional (time averaged) blood-gas sample ox |
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