Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution

Killer-cell immunoglobulin-like receptors (KIRs) are encoded by one of the most polymorphic families in the human genome. KIRs are expressed on natural killer (NK) cells, which have dual roles: (1) in fighting infection and (2) in reproduction, regulating hemochorial placentation. Uniquely among pri...

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Main Authors: Penman, B, Moffett, A, Chazara, O, Gupta, S, Parham, P
格式: Journal article
语言:English
出版: Springer Berlin Heidelberg 2016