Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution
Killer-cell immunoglobulin-like receptors (KIRs) are encoded by one of the most polymorphic families in the human genome. KIRs are expressed on natural killer (NK) cells, which have dual roles: (1) in fighting infection and (2) in reproduction, regulating hemochorial placentation. Uniquely among pri...
Main Authors: | Penman, B, Moffett, A, Chazara, O, Gupta, S, Parham, P |
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Format: | Journal article |
Language: | English |
Published: |
Springer Berlin Heidelberg
2016
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