Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms.

Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms.

BACKGROUND: Chloroquine resistance in Plasmodium falciparum malaria has been associated with pfcrt 76T (chloroquine resistance transporter gene) and pfmdr1 86Y (multidrug resistance gene 1) alleles. Pfcrt 76T enables transport of protonated chloroquine out of the parasites digestive vacuole resultin...

Podrobná bibliografie
Hlavní autoři:	Jovel, I, Ferreira, P, Veiga, M, Malmberg, M, Mårtensson, A, Kaneko, A, Zakeri, S, Murillo, C, Nosten, F, Björkman, A, Ursing, J
Médium:	Journal article
Jazyk:	English
Vydáno:	2014

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