Functional characterisation of naturally occurring mutations in human melanopsin

Melanopsin is a blue light-sensitive opsin photopigment involved in a range of non-image forming behaviours, including circadian photoentrainment and the pupil light response. Many naturally occurring genetic variants exist within the human melanopsin gene (OPN4), yet it remains unclear how these va...

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Bibliografiska uppgifter
Huvudupphovsmän: Rodgers, J, Peirson, SN, Hughes, S, Hankins, MW
Materialtyp: Journal article
Publicerad: Springer 2018