Identifying and exploiting genes that potentiate the evolution of antibiotic resistance

There is an urgent need to develop novel approaches for predicting and preventing the evolution of antibiotic resistance. Here, we show that the ability to evolve de novo resistance to a clinically important β-lactam antibiotic, ceftazidime, varies drastically across the genus Pseudomonas. This vari...

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Bibliographic Details
Main Authors: Gifford, D, Furio, V, Papkou, A, Vogwill, T, Oliver, A, MacLean, RC
Format: Journal article
Published: Nature Publishing Group 2018