In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway
HIV-1 virions assemble as immature particles containing Gag polyproteins that are processed by the viral protease into individual components, resulting in the formation of mature infectious particles. There are two competing models for the process of forming the mature HIV-1 core: the disassembly an...
Autores principales: | Ning, J, Erdemci-Tandogan, G, Yufenyuy, E, Wagner, J, Himes, B, Zhao, G, Aiken, C, Zandi, R, Zhang, P |
---|---|
Formato: | Journal article |
Lenguaje: | English |
Publicado: |
Springer Nature
2016
|
Ejemplares similares
-
Quenching protein dynamics interferes with HIV capsid maturation.
por: Wang, M, et al.
Publicado: (2017) -
Modeling the full length HIV-1 Gag polyprotein reveals the role of its p6 subunit in viral maturation and the effect of non-cleavage site mutations in protease drug resistance
por: Su, Chinh Tran-To, et al.
Publicado: (2020) -
Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons
por: Pauli, A, et al.
Publicado: (2008) -
Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons.
por: Pauli, A, et al.
Publicado: (2008) -
Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A
por: Ni, T, et al.
Publicado: (2020)