In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway

HIV-1 virions assemble as immature particles containing Gag polyproteins that are processed by the viral protease into individual components, resulting in the formation of mature infectious particles. There are two competing models for the process of forming the mature HIV-1 core: the disassembly an...

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Main Authors: Ning, J, Erdemci-Tandogan, G, Yufenyuy, E, Wagner, J, Himes, B, Zhao, G, Aiken, C, Zandi, R, Zhang, P
格式: Journal article
语言:English
出版: Springer Nature 2016