Karyotype and prognosis in childhood acute lymphoblastic leukemia (ALL) in the UK medical research council (MRC) ALL97 trial.

Detalhes bibliográficos
Main Authors:	Moorman, A, Richards, S, Martineau, M, Cheung, K, Robinson, H, Jalali, G, Broadfield, Z, Harris, R, Barber, K, Lilleyman, J, Kinsey, S, Eden, O, Vora, A, Mitchell, C, Harrison, C
Formato:	Conference item
Publicado em:	2003

Thioguanine-related veno-occlusive disease (VOD) of the liver in children with acute lymphoblastic leukaemia (ALL): Report from United Kingdom Medical Research Council (UK MRC) trial ALL97.
Por: Vora, A, et al.
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Thioguanine compared with mercaptopurine in childhood lymphoblastic leukaemia: Results of the United Kingdom medical research council randomised trial ALL97.
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MRC ALL97/99 - A randomized comparison of dexamethasone versus prednisolone and thioguanine versus mercaptopurine in the treatment of childhood acute lymphoblastic leukemia.
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Prognostic Relevance of Cytogenetics in Childhood Acute Lymphoblastic Leukaemia (ALL): Final Results From MRC ALL97.
Por: Moor-Man, A, et al.
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TEL-AML1 fusion in childhood acute lymphoblastic leukaemia (ALL): Demographics, clinical features, cytogenetic characteristics and prognosis
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The impact of risk stratification by early bone-marrow response in childhood lymphoblastic leukaemia: results from the United Kingdom Medical Research Council trial ALL97 and ALL97/99.
Por: Mitchell, C, et al.
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Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial.
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Three distinct subgroups of hypodiploidy in acute lymphoblastic leukemia in UK MRC trials.
Por: Harrison, C, et al.
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Acute lymphoblastic leukaemia has a poor outcome in children with Down syndrome due to infective death in remission - (Results of UK MRC ALL 97 trial).
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Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial.
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The clinical pharmacology of thioguanine vs. mercaptopurine in ALL97, a randomized trial for the treatment of childhood lymphoblastic leukaemia
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The thiopurine methyltransferase TPMT *1/*3A genotype is associated with a better treatment outcome in the UK ALL97 trial for childhood acute lymphoblastic leukaemia; TPMT heterozygosity is not associated with secondary cancers
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A third intensive block of treatment at 35 weeks improves outcome in childhood ALL: Preliminary results from the UKALLXI and ALL97 randomised trials.
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Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.
Por: Moorman, A, et al.
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Thioguanine versus mercaptopurine in ALL97: thiopurine metabolism and treatment outcome
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Improved Outcome for Children and Young Adults with T-Cell Acute Lymphoblastic Leukaemia (ALL): Results of the United Kingdom Medical Research Council (MRC) Trial UKALL 2003
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Karyotype is an independent prognostic factor in adult acute lymphoblastic leukaemia (ALL): Analysis of cytogenetic data from 1,235 patients on the medical research council (MRC) UKALLXII/Eastern cooperative oncology group (ECOG) 2993 trial.
Por: Moorman, A, et al.
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Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 trials.
Por: Moorman, A, et al.
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Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia.
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Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21).
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Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial.
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ETV6/RUNX1 fusion at diagnosis and relapse: some prognostic indications.
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Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
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Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial.
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Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome.
Por: Robinson, H, et al.
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Karyotype and prognosis in childhood acute lymphoblastic leukemia (ALL) in the UK medical research council (MRC) ALL97 trial.

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