Karyotype and prognosis in childhood acute lymphoblastic leukemia (ALL) in the UK medical research council (MRC) ALL97 trial.

Dettagli Bibliografici
Autori principali:	Moorman, A, Richards, S, Martineau, M, Cheung, K, Robinson, H, Jalali, G, Broadfield, Z, Harris, R, Barber, K, Lilleyman, J, Kinsey, S, Eden, O, Vora, A, Mitchell, C, Harrison, C
Natura:	Conference item
Pubblicazione:	2003

Thioguanine-related veno-occlusive disease (VOD) of the liver in children with acute lymphoblastic leukaemia (ALL): Report from United Kingdom Medical Research Council (UK MRC) trial ALL97.
di: Vora, A, et al.
Pubblicazione: (2002)

Variables affecting kinetics of minimal residual disease clearance in children with lymphoblastic leukaemia; Results of the United Kingdom Medical Research Council (UK MRC) protocols ALL97, ALL97/99 and ALL2003.
di: Vora, A, et al.
Pubblicazione: (2005)

Benefit of intensified treatment for all children with acute lymphoblastic leukaemia: results from MRC UKALL XI and MRC ALL97 randomised trials. UK Medical Research Council's Working Party on Childhood Leukaemia.
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Benefit of targeted intensification for NCI high risk childhood lymphoblastic leukaemia: Results of the United Kingdom medical research council trial ALL97 and ALL97/99.
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Pubblicazione: (2006)

Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial.
di: Mitchell, C, et al.
Pubblicazione: (2005)

Thioguanine compared with mercaptopurine in childhood lymphoblastic leukaemia: Results of the United Kingdom medical research council randomised trial ALL97.
di: Lennard, L, et al.
Pubblicazione: (2005)

MRC ALL97/99 - A randomized comparison of dexamethasone versus prednisolone and thioguanine versus mercaptopurine in the treatment of childhood acute lymphoblastic leukemia.
di: Mitchell, C, et al.
Pubblicazione: (2002)

Prognostic Relevance of Cytogenetics in Childhood Acute Lymphoblastic Leukaemia (ALL): Final Results From MRC ALL97.
di: Moor-Man, A, et al.
Pubblicazione: (2009)

TEL-AML1 fusion in childhood acute lymphoblastic leukaemia (ALL): Demographics, clinical features, cytogenetic characteristics and prognosis
di: Moorman, A, et al.
Pubblicazione: (2005)

The impact of risk stratification by early bone-marrow response in childhood lymphoblastic leukaemia: results from the United Kingdom Medical Research Council trial ALL97 and ALL97/99.
di: Mitchell, C, et al.
Pubblicazione: (2009)

Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial.
di: Ensor, H, et al.
Pubblicazione: (2011)

Three distinct subgroups of hypodiploidy in acute lymphoblastic leukemia in UK MRC trials.
di: Harrison, C, et al.
Pubblicazione: (2003)

Acute lymphoblastic leukaemia has a poor outcome in children with Down syndrome due to infective death in remission - (Results of UK MRC ALL 97 trial).
di: de la Fuente, J, et al.
Pubblicazione: (2005)

Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial.
di: Moorman, A, et al.
Pubblicazione: (2010)

The clinical pharmacology of thioguanine vs. mercaptopurine in ALL97, a randomized trial for the treatment of childhood lymphoblastic leukaemia
di: Lennard, L, et al.
Pubblicazione: (2008)

The thiopurine methyltransferase TPMT *1/*3A genotype is associated with a better treatment outcome in the UK ALL97 trial for childhood acute lymphoblastic leukaemia; TPMT heterozygosity is not associated with secondary cancers
di: Lennard, L, et al.
Pubblicazione: (2010)

Acute lymphoblastic leukaemia in infancy: experience in MRC UKALL trials. Report from the Medical Research Council Working Party on Childhood Leukaemia.
di: Chessells, J, et al.
Pubblicazione: (1994)

A third intensive block of treatment at 35 weeks improves outcome in childhood ALL: Preliminary results from the UKALLXI and ALL97 randomised trials.
di: Richards, S, et al.
Pubblicazione: (1998)

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.
di: Moorman, A, et al.
Pubblicazione: (2007)

Thioguanine versus mercaptopurine in ALL97: thiopurine metabolism and treatment outcome
di: Lennard, L, et al.
Pubblicazione: (2008)

Improved Outcome for Children and Young Adults with T-Cell Acute Lymphoblastic Leukaemia (ALL): Results of the United Kingdom Medical Research Council (MRC) Trial UKALL 2003
di: Vora, A, et al.
Pubblicazione: (2008)

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukaemia (ALL): Analysis of cytogenetic data from 1,235 patients on the medical research council (MRC) UKALLXII/Eastern cooperative oncology group (ECOG) 2993 trial.
di: Moorman, A, et al.
Pubblicazione: (2005)

Risk-directed treatment intensification significantly reduces the risk of relapse among children and adolescents with acute lymphoblastic leukemia and intrachromosomal amplification of chromosome 21: a comparison of the MRC ALL97/99 and UKALL2003 trials.
di: Moorman, A, et al.
Pubblicazione: (2013)

Gender and treatment outcome in childhood lymphoblastic leukaemia: report from the MRC UKALL trials.
di: Chessells, J, et al.
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Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia.
di: Harrison, C, et al.
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Continuing (maintenance) therapy in lymphoblastic leukaemia: lessons from MRC UKALL X. Medical Research Council Working Party in Childhood Leukaemia.
di: Chessells, J, et al.
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Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21).
di: Moorman, A, et al.
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Treatment of high risk leukaemia - Results of MRC childhood acute lymphoblastic leukaemia study MRC HR-1.
di: Kinsey, S, et al.
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Clinical significance of blast cell karyotype change at relapse of childhood ALL.
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Testicular irradiation in childhood lymphoblastic leukaemia. Medical Research Council Working Party on Leukemia in Childhoods.
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Outcome heterogeneity in childhood high-hyperdiploid acute lymphoblastic leukemia.
di: Moorman, A, et al.
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The Spectrum and Prognostic Relevance of Additional Abnormalities, Involving 12p and 21q, in Children with ETV6-RUNX1 Positive Acute Lymphoblastic Leukaemia (ALL)
di: Moorman, A, et al.
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Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial.
di: Vora, A, et al.
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ETV6/RUNX1 fusion at diagnosis and relapse: some prognostic indications.
di: Martineau, M, et al.
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Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172).
di: Hill, F, et al.
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Temporal changes in the incidence and pattern of central nervous system relapses in children with acute lymphoblastic leukaemia treated on four consecutive Medical Research Council trials, 1985-2001.
di: Krishnan, S, et al.
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Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
di: Ramanujachar, R, et al.
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Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial.
di: Sive, J, et al.
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Analysis of the immunophenotype of children treated on the Medical Research Council United Kingdom Acute Lymphoblastic Leukaemia Trial XI (MRC UKALLXI). Medical Research Council Childhood Leukaemia Working Party.
di: Hann, I, et al.
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Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome.
di: Robinson, H, et al.
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Karyotype and prognosis in childhood acute lymphoblastic leukemia (ALL) in the UK medical research council (MRC) ALL97 trial.

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