Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.
An IL-1-stimulated protein kinase cascade resulting in phosphorylation of the small heat shock protein hsp27 has been identified in KB cells. It is distinct from the p42 MAP kinase cascade. An upstream activator kinase phosphorylated a 40 kDa kinase (p40) upon threonine and tyrosine residues, which...
Main Authors: | Freshney, N, Rawlinson, L, Guesdon, F, Jones, E, Cowley, S, Hsuan, J, Saklatvala, J |
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Format: | Journal article |
Language: | English |
Published: |
1994
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