Signalling cross talk of the HIF system: involvement of the FIH protein.
Cellular and systemic oxygen homeostasis is regulated by an oxygen-sensitive signalling pathway centred on a transcription factor known as Hypoxia Inducible Factor (HIF). Regulation of HIF activity and protein stability is mediated by a family of hydroxylases that act as oxygen sensors due to the de...
Hlavní autoři: | , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2009
|