Signalling cross talk of the HIF system: involvement of the FIH protein.

Cellular and systemic oxygen homeostasis is regulated by an oxygen-sensitive signalling pathway centred on a transcription factor known as Hypoxia Inducible Factor (HIF). Regulation of HIF activity and protein stability is mediated by a family of hydroxylases that act as oxygen sensors due to the de...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Coleman, M, Ratcliffe, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2009