Signalling cross talk of the HIF system: involvement of the FIH protein.
Cellular and systemic oxygen homeostasis is regulated by an oxygen-sensitive signalling pathway centred on a transcription factor known as Hypoxia Inducible Factor (HIF). Regulation of HIF activity and protein stability is mediated by a family of hydroxylases that act as oxygen sensors due to the de...
| Main Authors: | , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
2009
|