Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors.

Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors.

It has been proposed that antibodies can mimic the binding of a receptor to its ligand and that anti-idiotype antibodies raised against such antibodies can be used to identify the receptor. A large number of antibodies have been raised against CD4, the receptor on T cells for the envelope glycoprote...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক:	Davis, S, Schockmel, G, Somoza, C, Buck, D, Healey, D, Rieber, E, Reiter, C, Williams, A
বিন্যাস:	Journal article
ভাষা:	English
প্রকাশিত:	1992

অনুরূপ উপাদানগুলি

The recognition of chimeras of rat and human CD4 by HIV-1 gp120 and by monoclonal antibodies.
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প্রকাশিত: (1993)

Construction of a binding site for human immunodeficiency virus type 1 gp120 in rat CD4.
অনুযায়ী: Schockmel, G, অন্যান্য
প্রকাশিত: (1992)

A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection.
অনুযায়ী: Simon, J, অন্যান্য
প্রকাশিত: (1993)

Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response
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প্রকাশিত: (2008-07-01)

Fusion Complexes and CD4-independent gp120s for the Induction of HIV-1 Neutralizing Antibodies
অনুযায়ী: Lopalco L, অন্যান্য
প্রকাশিত: (2005-12-01)

Role of anti-CD4-binding site antibodies in modulating gp120-specific CD4 T cell and antibody responses
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প্রকাশিত: (2006-12-01)

Monoclonal antibodies to HIV-1 gp120: a request.
অনুযায়ী: Moore, J, অন্যান্য
প্রকাশিত: (1993)

Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS
অনুযায়ী: Veljković Nevena V.
প্রকাশিত: (2005-01-01)

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site
অনুযায়ী: Dai K, অন্যান্য
প্রকাশিত: (2012-09-01)

Enhancement of soluble CD4-mediated HIV neutralization and gp 120 binding by CD4 autoantibodies and monoclonal antibodies.
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প্রকাশিত: (1990)

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.
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প্রকাশিত: (2017-01-01)

Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.
অনুযায়ী: Moore, J, অন্যান্য
প্রকাশিত: (1995)

Engineered gp120 immunogens that elicit VRC01-like antibodies by vaccination
অনুযায়ী: Mata-Fink, Jordi, অন্যান্য
প্রকাশিত: (2013)

Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.
অনুযায়ী: Mondor, I, অন্যান্য
প্রকাশিত: (1998)

Glycan microheterogeneity at the PGT135 antibody recognition site on HIV-1 gp120 reveals a molecular mechanism for neutralization resistance.
অনুযায়ী: Pritchard, L, অন্যান্য
প্রকাশিত: (2015)

Characterization of gp120 and Its Single-chain Derivatives, gp120-CD4 and gp120-M9: Implications for Targeting the CD4i Epitope in HIV-1 Vaccine Design
অনুযায়ী: Shiver John
প্রকাশিত: (2005-12-01)

A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies
অনুযায়ী: Evan M. Cale, অন্যান্য
প্রকাশিত: (2024-12-01)

Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
অনুযায়ী: Jean-Philippe Julien, অন্যান্য
প্রকাশিত: (2013-01-01)

Super Potent Bispecific Llama VHH Antibodies Neutralize HIV via a Combination of gp41 and gp120 Epitopes
অনুযায়ী: Nika M. Strokappe, অন্যান্য
প্রকাশিত: (2019-06-01)

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7.
অনুযায়ী: Sakaorat Lertjuthaporn, অন্যান্য
প্রকাশিত: (2018-08-01)

Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41.
অনুযায়ী: Mei-Yun Zhang, অন্যান্য
প্রকাশিত: (2012-01-01)

Engineering of HIV gp120 by yeast surface display for neutralizing antibody characterization and immunogen design
অনুযায়ী: Mata-Fink, Jordi
প্রকাশিত: (2013)

Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores
অনুযায়ী: Jidnyasa Ingale, অন্যান্য
প্রকাশিত: (2015-10-01)

A region in domain 1 of CD4 distinct from the primary gp120 binding site is involved in HIV infection and virus-mediated fusion.
অনুযায়ী: Truneh, A, অন্যান্য
প্রকাশিত: (1991)

Structural definition for a new modality of broad and potent antibody neutralization at the CD4-binding site on HIV-1 gp120
অনুযায়ী: Zhou T, অন্যান্য
প্রকাশিত: (2012-09-01)

Rapid development of cross-clade neutralizing antibody responses after clade B gp120/gp140 protein priming and clade c gp140 protein boosting
অনুযায়ী: Spearman P, অন্যান্য
প্রকাশিত: (2012-09-01)

Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation.
অনুযায়ী: Poignard, P, অন্যান্য
প্রকাশিত: (1996)

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
অনুযায়ী: Astronomo, R, অন্যান্য
প্রকাশিত: (2008)

Functional epitope analysis of the human CD4 molecule. The MHC class II-dependent activation of resting T cells is inhibited by monoclonal antibodies to CD4 regardless whether or not they recognize epitopes involved in the binding of MHC class II or HIV gp120.
অনুযায়ী: Merkenschlager, M, অন্যান্য
প্রকাশিত: (1990)

Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and co-receptor binding sites of HIV-1 gp120
অনুযায়ী: Matz J, অন্যান্য
প্রকাশিত: (2012-09-01)

Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies.
অনুযায়ী: Moore, J, অন্যান্য
প্রকাশিত: (1994)

The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies
অনুযায়ী: Dueñas-Decamp Maria J, অন্যান্য
প্রকাশিত: (2012-01-01)

Structural basis for germline gene usage of a potent class of antibodies targeting the CD4 binding site of HIV-1 gp120
অনুযায়ী: West AP, অন্যান্য
প্রকাশিত: (2012-09-01)

Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1.
অনুযায়ী: Simon, J, অন্যান্য
প্রকাশিত: (1997)

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
অনুযায়ী: Andrew J Borst, অন্যান্য
প্রকাশিত: (2018-11-01)

Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.
অনুযায়ী: Esser, M, অন্যান্য
প্রকাশিত: (1999)

Glycan modifications to the gp120 immunogens used in the RV144 vaccine trial improve binding to broadly neutralizing antibodies.
অনুযায়ী: Rachel C Doran, অন্যান্য
প্রকাশিত: (2018-01-01)

Characterization of a Large Panel of Rabbit Monoclonal Antibodies against HIV-1 gp120 and Isolation of Novel Neutralizing Antibodies against the V3 Loop.
অনুযায়ী: Yali Qin, অন্যান্য
প্রকাশিত: (2015-01-01)

Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed on Yeast
অনুযায়ী: Mata-Fink, Jordi, অন্যান্য
প্রকাশিত: (2015)

Reciprocal recognition of an HLA-Cw4-restricted HIV-1 gp120 epitope by CD8+ T cells and NK cells.
অনুযায়ী: Thananchai, H, অন্যান্য
প্রকাশিত: (2009)