Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors.
It has been proposed that antibodies can mimic the binding of a receptor to its ligand and that anti-idiotype antibodies raised against such antibodies can be used to identify the receptor. A large number of antibodies have been raised against CD4, the receptor on T cells for the envelope glycoprote...
Κύριοι συγγραφείς: | Davis, S, Schockmel, G, Somoza, C, Buck, D, Healey, D, Rieber, E, Reiter, C, Williams, A |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
1992
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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The recognition of chimeras of rat and human CD4 by HIV-1 gp120 and by monoclonal antibodies.
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Construction of a binding site for human immunodeficiency virus type 1 gp120 in rat CD4.
ανά: Schockmel, G, κ.ά.
Έκδοση: (1992) -
A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection.
ανά: Simon, J, κ.ά.
Έκδοση: (1993) -
Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response
ανά: Hioe Catarina E, κ.ά.
Έκδοση: (2008-07-01) -
Fusion Complexes and CD4-independent gp120s for the Induction of HIV-1 Neutralizing Antibodies
ανά: Lopalco L, κ.ά.
Έκδοση: (2005-12-01)