Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors.

It has been proposed that antibodies can mimic the binding of a receptor to its ligand and that anti-idiotype antibodies raised against such antibodies can be used to identify the receptor. A large number of antibodies have been raised against CD4, the receptor on T cells for the envelope glycoprote...

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Détails bibliographiques
Auteurs principaux: Davis, S, Schockmel, G, Somoza, C, Buck, D, Healey, D, Rieber, E, Reiter, C, Williams, A
Format: Journal article
Langue:English
Publié: 1992