Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.

<h4>Background</h4> <p>Loss of proprotein convertase subtilisin/kexin type 5 (Pcsk5) results in multiple developmental anomaliesincluding cardiac malformations, caudal regression, pre-sacral mass, renal agenesis, anteroposterior patterning defects, and tracheo-oesophageal and anor...

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Bibliographic Details
Main Authors: Szumska, D, Cioroch, M, Keeling, A, Prat, A, Seidah, NG, Bhattacharya, S
Format: Journal article
Language:English
Published: BioMed Central 2017