A randomized, double-blind, placebo-controlled trial of repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis

A randomized, double-blind, placebo-controlled trial of repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis

מידע ביבליוגרפי
Main Authors:	Alton, E, Armstrong, D, Bayfield, K, Bilton, D, Boyd, A, Cheng, S, Cunningham, S, Davies, J, Elgmati, H, Gill, D, Greening, A, Griesenbach, U, Harman, K, Higgins, T, Hyde, S, Innes, J, McGovern, M, Murray, G, Porteous, D, Saunders, C, Scheule, R, Simmonds, N, Soussi, S, Sumner-Jones, S, Waller, M
פורמט:	Conference item
שפה:	English
יצא לאור:	Wiley 2015

פריטים דומים

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial
מאת: Alton, EWFW, et al.
יצא לאור: (2015)

SAFETY AND EXPRESSION OF A SINGLE DOSE OF LIPID-MEDIATED CFTR GENE THERAPY TO THE UPPER AND LOWER AIRWAYS OF PATIENTS WITH CF
מאת: Davies, J, et al.
יצא לאור: (2011)

Self-reactive CFTR T cells in humans: implications for gene therapy.
מאת: Calcedo, R, et al.
יצא לאור: (2013)

SAFETY AND EXPRESSION OF A SINGLE DOSE OF LIPID-MEDIATED CFTR GENE THERAPY TO THE UPPER AND LOWER AIRWAYS OF PATIENTS WITH CYSTIC FIBROSIS
מאת: Davies, G, et al.
יצא לאור: (2011)

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis
מאת: Alton, EWFW, et al.
יצא לאור: (2016)

REPEAT ADMINISTRATION OF GL67A/PGM169 IS FEASIBLE, SAFE, AND PRODUCES ENDOGENOUS LEVELS OF CFTR EXPRESSION AFTER 12 DOSES
מאת: Alton, E, et al.
יצא לאור: (2012)

Cumulative CFTR expression following repeated aerosol delivery of non-viral pGM169/GL67A formulation to mouse lung
מאת: Alton, E, et al.
יצא לאור: (2012)

Assessment of CFTR function after gene transfer in vitro and in vivo.
מאת: Griesenbach, U, et al.
יצא לאור: (2008)

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis
מאת: Eric WFW Alton, et al.
יצא לאור: (2016-07-01)

A PHASE 2B DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF NON-VIRAL MEDIATED GENE THERAPY FOR CF
מאת: Alton, E, et al.
יצא לאור: (2013)

LONGITUDINAL ASSESSMENT OF BIOMARKERS FOR CLINICAL TRIALS OF NOVEL THERAPEUTIC AGENTS; THE RUN-IN STUDY
מאת: Alton, E, et al.
יצא לאור: (2010)

LONGITUDINAL ASSESSMENT OF BIOMARKERS FOR CLINICAL TRIALS OF NOVEL THERAPEUTIC AGENTS: THE RUN-IN STUDY
מאת: Alton, E, et al.
יצא לאור: (2010)

Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity.
מאת: Holder, E, et al.
יצא לאור: (2010)

TOXICOLOGY STUDIES IN SUPPORT OF THE UK CF GENE THERAPY CONSORTIUM'S MULTI-DOSE CLINICAL TRIAL
מאת: Griesenbach, U, et al.
יצא לאור: (2011)

A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis
מאת: Alton, E, et al.
יצא לאור: (2013)

A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis.
מאת: Alton, E, et al.
יצא לאור: (2013)

UPDATE ON THE UK CF GENE THERAPY CONSORTIUM MULTIDOSE, NON-VIRAL, GENE THERAPY TRIAL
מאת: Alton, E, et al.
יצא לאור: (2012)

UPDATE ON THE UK CF GENE THERAPY CONSORTIUM MULTIDOSE, NON-VIRAL, GENE THERAPY TRIAL
מאת: Alton, E, et al.
יצא לאור: (2012)

Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung.
מאת: Alton, E, et al.
יצא לאור: (2014)

Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung
מאת: Alton, E, et al.
יצא לאור: (2014)

Development of an immunocytochemical assay to detect human CFTR expression following gene therapy
מאת: Davidson, H, et al.
יצא לאור: (2008)

Adenovirus-mediated in utero expression of CFTR does not improve survival of CFTR knockout mice.
מאת: Davies, L, et al.
יצא לאור: (2008)

An immunocytochemical assay to detect human CFTR expression following gene transfer.
מאת: Davidson, H, et al.
יצא לאור: (2009)

EVALUATION OF SAFETY AND GENE EXPRESSION WITH A SINGLE DOSE OF PGM169/GL67A ADMINISTERED TO THE NOSE AND LUNG OF INDIVIDUALS WITH CYSTIC FIBROSIS: THE UK CF GENE THERAPY CONSORTIUM "PILOT STUDY''
מאת: Davies, J, et al.
יצא לאור: (2009)

EVALUATION OF SAFETY AND GENE EXPRESSION WITH A SINGLE DOSE OF PGM169/GL67A ADMINISTERED TO THE NOSE AND LUNG OF INDIVIDUALS WITH CF: THE UK CF GENE THERAPY CONSORTIUM "PILOT STUDY"
מאת: Davies, J, et al.
יצא לאור: (2009)

The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep
מאת: Alton, E, et al.
יצא לאור: (2013)

The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep.
מאת: Alton, E, et al.
יצא לאור: (2013)

Sendai virus-mediated CFTR gene transfer to the airway epithelium.
מאת: Ferrari, S, et al.
יצא לאור: (2007)

DEVELOPMENT, PRODUCTION AND EVALUATION OF CLINICAL GRADE CFTR EXPRESSION PLASMID FOR CF LUNG GENE THERAPY
מאת: Gill, DR, et al.
יצא לאור: (2010)

Decalogue of nebulisation
מאת: Adam J. Sybilski
יצא לאור: (2019-07-01)

Low levels of CFTR gene transfer with F/HN pseudotyped lentivirus are sufficient to generate ion transport correction in airway cell cultures from cystic fibrosis patients
מאת: Sergijenko, A, et al.
יצא לאור: (2020)

Update on the UK CF Gene Therapy Consortium Multidoes, non-viral, gene therapy trial
מאת: Alton, E, et al.
יצא לאור: (2012)

UKCF gene therapy consortium tracking study: Sputum and serum calprotectin are useful novel measurements in CF exacerbation
מאת: Gray, R, et al.
יצא לאור: (2007)

Assessment of the air-liquid interface culture model as a tool to validate efficacy of a rSIV.F/HN-CFTR vector
מאת: Sergijenko, A, et al.
יצא לאור: (2021)

Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium.
מאת: Maria D I Manunta, et al.
יצא לאור: (2011-01-01)

Genetic medicines for CF: Hype versus reality
מאת: Alton, E, et al.
יצא לאור: (2016)

Nebulised Dexmedetomidine versus Nebulised Lignocaine in Blunting the Haemodynamic Response to Laryngoscopy and Endotracheal Intubation: A Randomised Control Study
מאת: Anju Rani, et al.
יצא לאור: (2024-06-01)

Safety and tolerability of bronchoscopic and nebulised administration of bacteriophage
מאת: Jagdev Singh, et al.
יצא לאור: (2024-10-01)

Pharmacokinetic prediction of nebulised polymyxin for pulmonary delivery
מאת: Hu Tian, et al.
יצא לאור: (2023-01-01)

Non-viral CFTR gene delivery to the lungs of Cystic Fibrosis patients
מאת: Hyde, S
יצא לאור: (2013)