Gating-like motions and wall porosity in a DNA nanopore scaffold revealed by molecular simulations
Recently developed synthetic membrane pores composed of folded DNA enrich the current range of natural and engineered protein pores and of nonbiogenic channels. Here we report all-atom molecular dynamics simulations of a DNA nanotube (DNT) pore scaffold to gain fundamental insight into its atomic st...
Main Authors: | Sansom, M, Maingi, V, Lelimousin, M, Howorka, S |
---|---|
Format: | Journal article |
Published: |
American Chemical Society
2015
|
Similar Items
-
Stability and Dynamics of Membrane-Spanning DNA Nanopores
by: Maingi, V, et al.
Published: (2017) -
Structural and Functional Stability of DNA Nanopores in Biological Media
by: Jonathan R. Burns, et al.
Published: (2019-03-01) -
A hydrophobic gating mechanism for nanopores
by: Beckstein, O, et al.
Published: (2001) -
Water and hydrophobic gates in ion channels and nanopores
by: Rao, S, et al.
Published: (2018) -
DNA scaffolds support stable and uniform peptide nanopores
by: Spruijt, E, et al.
Published: (2018)