Preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.

The preparation of capsules for medical and industrial use can be achieved via several conventional routes, yielding either hard or soft receptacles, depending on the type and the content of the material to be encapsulated. Together with tablets, capsules are amongst the most commonly used means of...

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Principais autores: Nangrejo, M, Ahmad, Z, Stride, E, Edirisinghe, M, Colombo, P
Formato: Journal article
Idioma:English
Publicado em: 2008
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author Nangrejo, M
Ahmad, Z
Stride, E
Edirisinghe, M
Colombo, P
author_facet Nangrejo, M
Ahmad, Z
Stride, E
Edirisinghe, M
Colombo, P
author_sort Nangrejo, M
collection OXFORD
description The preparation of capsules for medical and industrial use can be achieved via several conventional routes, yielding either hard or soft receptacles, depending on the type and the content of the material to be encapsulated. Together with tablets, capsules are amongst the most commonly used means of administering medication and this makes progress in capsule preparation technology a key area of drug delivery research. Here we uncover new technology for the preparation of capsules with porous chambers. The novelty is signified in the use of an electrohydrodynamic process engineering route and its potential is elucidated using a polymeric material; polymethylsilsesquioxane, which can be converted into an identical ceramic form by means of simple pyrolysis. Thus, both polymeric and ceramic capsules have been prepared. The effects of process control parameters such as the applied voltage and flow rate, on the characteristics of the capsules prepared are discussed.
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spelling oxford-uuid:f7a2fdba-dc6f-48e2-b2d1-146f82869c262022-03-27T12:44:13ZPreparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f7a2fdba-dc6f-48e2-b2d1-146f82869c26EnglishSymplectic Elements at Oxford2008Nangrejo, MAhmad, ZStride, EEdirisinghe, MColombo, PThe preparation of capsules for medical and industrial use can be achieved via several conventional routes, yielding either hard or soft receptacles, depending on the type and the content of the material to be encapsulated. Together with tablets, capsules are amongst the most commonly used means of administering medication and this makes progress in capsule preparation technology a key area of drug delivery research. Here we uncover new technology for the preparation of capsules with porous chambers. The novelty is signified in the use of an electrohydrodynamic process engineering route and its potential is elucidated using a polymeric material; polymethylsilsesquioxane, which can be converted into an identical ceramic form by means of simple pyrolysis. Thus, both polymeric and ceramic capsules have been prepared. The effects of process control parameters such as the applied voltage and flow rate, on the characteristics of the capsules prepared are discussed.
spellingShingle Nangrejo, M
Ahmad, Z
Stride, E
Edirisinghe, M
Colombo, P
Preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.
title Preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.
title_full Preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.
title_fullStr Preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.
title_full_unstemmed Preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.
title_short Preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process.
title_sort preparation of polymeric and ceramic porous capsules by a novel electrohydrodynamic process
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