Transcriptomic analysis reveals a critical role for activating G s α mutations in spontaneous feline hyperthyroidism

Feline hyperthyroidism (FHT) is a debilitating disease affecting > 10% of elderly cats. It is generally characterised by chronic elevation of thyroid hormone in the absence of circulating TSH. Understanding of the molecular pathogenesis of FHT is currently limited. However, FHT shares clinical an...

Descrición completa

Detalles Bibliográficos
Main Authors: Hiron, TK, Aguiar, J, Williams, JM, Falcone, S, Norman, PA, Elliott, J, Fowkes, RC, Syme, HM, Davison, LJ
Formato: Journal article
Idioma:English
Publicado: Nature Research 2024