Transcriptomic analysis reveals a critical role for activating G s α mutations in spontaneous feline hyperthyroidism

Feline hyperthyroidism (FHT) is a debilitating disease affecting > 10% of elderly cats. It is generally characterised by chronic elevation of thyroid hormone in the absence of circulating TSH. Understanding of the molecular pathogenesis of FHT is currently limited. However, FHT shares clinical an...

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Detalhes bibliográficos
Principais autores: Hiron, TK, Aguiar, J, Williams, JM, Falcone, S, Norman, PA, Elliott, J, Fowkes, RC, Syme, HM, Davison, LJ
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2024