Identification of an isomer impurity in piperaquine drug substance.

Identification of an isomer impurity in piperaquine drug substance.

A significant contaminant of the antimalarial drug piperaquine (1,3-bis-[4-(7-chloroquinolyl-4)-piperazinyl-1]propane) has been identified using liquid chromatography-mass spectrometry (LC-MS) and 2D NMR spectroscopy (1H-1H COSY, 1H-13C HSQC, 1H-13C HMBC). The impurity was identified as the position...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Lindegårdh, N, Giorgi, F, Galletti, B, Di Mattia, M, Quaglia, M, Carnevale, D, White, N, Mazzanti, A, Day, N
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2006

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