Single-cell RNAseq profiling of early heart developmental physiology
The heart is the first organ to form and function during mammalian development. Recently we established that in the mouse embryo, spontaneous asynchronous calcium oscillations (SACOs) occour in the cardiac crescent prior to the onset of cardiac contractions. Blocking Sodium Calcium Exchanger (NCX1)...
| Main Authors: | , , , , , |
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| Format: | Conference item |
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Elsevier
2017
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| _version_ | 1797104663601872896 |
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| author | Miranda, AMA Tyser, RCV Riley, PR Scialdone, A Marioni, J Srinivas, S |
| author_facet | Miranda, AMA Tyser, RCV Riley, PR Scialdone, A Marioni, J Srinivas, S |
| author_sort | Miranda, AMA |
| collection | OXFORD |
| description | The heart is the first organ to form and function during mammalian development. Recently we established that in the mouse embryo, spontaneous asynchronous calcium oscillations (SACOs) occour in the cardiac crescent prior to the onset of cardiac contractions. Blocking Sodium Calcium Exchanger (NCX1) function inhibits these oscillations and cardiac differentiation. |
| first_indexed | 2024-03-07T06:36:47Z |
| format | Conference item |
| id | oxford-uuid:f7eca7d8-51f5-497e-b5dd-c984f43cf614 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T06:36:47Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:f7eca7d8-51f5-497e-b5dd-c984f43cf6142022-03-27T12:46:21ZSingle-cell RNAseq profiling of early heart developmental physiologyConference itemhttp://purl.org/coar/resource_type/c_5794uuid:f7eca7d8-51f5-497e-b5dd-c984f43cf614Symplectic Elements at OxfordElsevier2017Miranda, AMATyser, RCVRiley, PRScialdone, AMarioni, JSrinivas, SThe heart is the first organ to form and function during mammalian development. Recently we established that in the mouse embryo, spontaneous asynchronous calcium oscillations (SACOs) occour in the cardiac crescent prior to the onset of cardiac contractions. Blocking Sodium Calcium Exchanger (NCX1) function inhibits these oscillations and cardiac differentiation. |
| spellingShingle | Miranda, AMA Tyser, RCV Riley, PR Scialdone, A Marioni, J Srinivas, S Single-cell RNAseq profiling of early heart developmental physiology |
| title | Single-cell RNAseq profiling of early heart developmental physiology |
| title_full | Single-cell RNAseq profiling of early heart developmental physiology |
| title_fullStr | Single-cell RNAseq profiling of early heart developmental physiology |
| title_full_unstemmed | Single-cell RNAseq profiling of early heart developmental physiology |
| title_short | Single-cell RNAseq profiling of early heart developmental physiology |
| title_sort | single cell rnaseq profiling of early heart developmental physiology |
| work_keys_str_mv | AT mirandaama singlecellrnaseqprofilingofearlyheartdevelopmentalphysiology AT tyserrcv singlecellrnaseqprofilingofearlyheartdevelopmentalphysiology AT rileypr singlecellrnaseqprofilingofearlyheartdevelopmentalphysiology AT scialdonea singlecellrnaseqprofilingofearlyheartdevelopmentalphysiology AT marionij singlecellrnaseqprofilingofearlyheartdevelopmentalphysiology AT srinivass singlecellrnaseqprofilingofearlyheartdevelopmentalphysiology |