Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.

The dimeric cell-surface glycoprotein CD8 is crucial to the positive selection of cytotoxic T cells in the thymus. The homodimer CD8alpha(alpha) or the heterodimer alpha beta stabilizes the interaction of the T-cell antigen receptor (TCR) with major histocompatibility complex (MHC) class I/peptide b...

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Dettagli Bibliografici
Autori principali: Gao, G, Tormo, J, Gerth, U, Wyer, JR, McMichael, A, Stuart, D, Bell, J, Jones, E, Jakobsen, B
Natura: Journal article
Lingua:English
Pubblicazione: 1997

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