Analysis of B-cell immune tolerance induction using transgenic mice.
Over the past 15 yr, the use of transgenic mice has led to significant advances in our understanding of immunological tolerance. In a normal repertoire the number of B cells with a single antigen receptor specificity is very small, making the study of their fate difficult. In contrast, animals that...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2004
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