Analysis of B-cell immune tolerance induction using transgenic mice.
Over the past 15 yr, the use of transgenic mice has led to significant advances in our understanding of immunological tolerance. In a normal repertoire the number of B cells with a single antigen receptor specificity is very small, making the study of their fate difficult. In contrast, animals that...
Autores principales: | , |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2004
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