The association of Plk1 with the astrin–kinastrin complex promotes formation and maintenance of a metaphase plate
Errors in mitotic chromosome segregation can lead to DNA damage and aneuploidy, both hallmarks of cancer. To achieve synchronous error-free segregation, mitotic chromosomes must align at the metaphase plate with stable amphitelic attachments to microtubules emanating from opposing spindle poles. The...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Company of Biologists
2021
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