NMDA receptor blockers facilitate and impair learning via different mechanisms.
The NMDA receptor blockers CGP 37849 (competitive) and MK 801 (noncompetitive) improve retention performance in the step-down passive avoidance situation but impair it in the step-through dark avoidance. It is suggested that the drugs in the two tasks act on different underlying processes. Whereas t...
Main Authors: | Mondadori, C, Weiskrantz, L |
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Format: | Journal article |
Language: | English |
Published: |
1993
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