SARS transmission in Vietnam outside of the health-care setting.
To evaluate the risk of transmission of SARS coronavirus outside of the health-care setting, close household and community contacts of laboratory-confirmed SARS cases were identified and followed up for clinical and laboratory evidence of SARS infection. Individual- and household-level risk factors...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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| _version_ | 1797104697150013440 |
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| author | Tuan, P Horby, P Dinh, P Mai, LT Zambon, M Shah, J Huy, V Bloom, S Gopal, R Comer, J Plant, A |
| author_facet | Tuan, P Horby, P Dinh, P Mai, LT Zambon, M Shah, J Huy, V Bloom, S Gopal, R Comer, J Plant, A |
| author_sort | Tuan, P |
| collection | OXFORD |
| description | To evaluate the risk of transmission of SARS coronavirus outside of the health-care setting, close household and community contacts of laboratory-confirmed SARS cases were identified and followed up for clinical and laboratory evidence of SARS infection. Individual- and household-level risk factors for transmission were investigated. Nine persons with serological evidence of SARS infection were identified amongst 212 close contacts of 45 laboratory-confirmed SARS cases (secondary attack rate 4.2%, 95% CI 1.5-7). In this cohort, the average number of secondary infections caused by a single infectious case was 0.2. Two community contacts with laboratory evidence of SARS coronavirus infection had mild or sub-clinical infection, representing 3% (2/65) of Vietnamese SARS cases. There was no evidence of transmission of infection before symptom onset. Physically caring for a symptomatic laboratory-confirmed SARS case was the only independent risk factor for SARS transmission (OR 5.78, 95% CI 1.23-24.24). |
| first_indexed | 2024-03-07T06:37:13Z |
| format | Journal article |
| id | oxford-uuid:f80f4bcf-0207-4f91-bce4-799c92f68489 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:37:13Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:f80f4bcf-0207-4f91-bce4-799c92f684892022-03-27T12:47:34ZSARS transmission in Vietnam outside of the health-care setting.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f80f4bcf-0207-4f91-bce4-799c92f68489EnglishSymplectic Elements at Oxford2007Tuan, PHorby, PDinh, PMai, LTZambon, MShah, JHuy, VBloom, SGopal, RComer, JPlant, ATo evaluate the risk of transmission of SARS coronavirus outside of the health-care setting, close household and community contacts of laboratory-confirmed SARS cases were identified and followed up for clinical and laboratory evidence of SARS infection. Individual- and household-level risk factors for transmission were investigated. Nine persons with serological evidence of SARS infection were identified amongst 212 close contacts of 45 laboratory-confirmed SARS cases (secondary attack rate 4.2%, 95% CI 1.5-7). In this cohort, the average number of secondary infections caused by a single infectious case was 0.2. Two community contacts with laboratory evidence of SARS coronavirus infection had mild or sub-clinical infection, representing 3% (2/65) of Vietnamese SARS cases. There was no evidence of transmission of infection before symptom onset. Physically caring for a symptomatic laboratory-confirmed SARS case was the only independent risk factor for SARS transmission (OR 5.78, 95% CI 1.23-24.24). |
| spellingShingle | Tuan, P Horby, P Dinh, P Mai, LT Zambon, M Shah, J Huy, V Bloom, S Gopal, R Comer, J Plant, A SARS transmission in Vietnam outside of the health-care setting. |
| title | SARS transmission in Vietnam outside of the health-care setting. |
| title_full | SARS transmission in Vietnam outside of the health-care setting. |
| title_fullStr | SARS transmission in Vietnam outside of the health-care setting. |
| title_full_unstemmed | SARS transmission in Vietnam outside of the health-care setting. |
| title_short | SARS transmission in Vietnam outside of the health-care setting. |
| title_sort | sars transmission in vietnam outside of the health care setting |
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