Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation

Axially chiral biaryls, as exemplified by 1,1’-bi-2-naphthol (BINOL), are key components of catalysts, natural products and medicines. These materials are synthesized conventionally in enantioenriched form through metal- mediated cross coupling, de novo construction of an aromatic ring, point-to-axi...

詳細記述

書誌詳細
主要な著者: Jolliffe, J, Armstrong, R, Smith, M
フォーマット: Journal article
出版事項: Nature Publishing Group 2017