Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation
Axially chiral biaryls, as exemplified by 1,1’-bi-2-naphthol (BINOL), are key components of catalysts, natural products and medicines. These materials are synthesized conventionally in enantioenriched form through metal- mediated cross coupling, de novo construction of an aromatic ring, point-to-axi...
| Үндсэн зохиолчид: | , , |
|---|---|
| Формат: | Journal article |
| Хэвлэсэн: |
Nature Publishing Group
2017
|