Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide.
AIMS/HYPOTHESIS: To investigate the tissue specificity of gliclazide for cloned beta-cell, cardiac and smooth muscle ATP-sensitive K-channels (K(ATP) channels). These channels share a common pore-forming subunit, Kir6.2, which associates with different sulphonylurea receptor isoforms (SUR1 in beta-c...
Huvudupphovsmän: | , |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
1999
|