MAIT cells: new guardians of the liver

MAIT cells: new guardians of the liver

The liver is an important immunological organ that remains sterile and tolerogenic in homeostasis, despite continual exposure to non-self food and microbial-derived products from the gut. However, where intestinal mucosal defenses are breached or in the presence of a systemic infection, the liver ac...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Kurioka, A, Walker, L, Klenerman, P, Willberg, C
Format:	Journal article
Język:	English
Wydane:	Nature Publishing Group 2016

Podobne zapisy

Erratum: MAIT cells: new guardians of the liver.
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MAIT cells induce proinflammatory cytokine production in monocytes through the secretion of granzymes A and K
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MAIT cells induce proinflammatory cytokine production in monocytes through the secretion of granzymes A and K
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Mucosal-associated invariant T (MAIT) cells: new players in anti-bacterial immunity
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TLR signaling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells
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High MDR‐1 expression by MAIT cells confers resistance to cytotoxic but not immunosuppressive MDR‐1 substrates
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Human MAIT cell activation in vitro
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Human MAIT cells show metabolic quiescence with rapid glucose-dependent upregulation of granzyme B upon stimulation
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MAIT cells: the end of the beginning?
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MAIT cells in health and disease
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MAIT cells are activated during human viral infections
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MAIT cells are enriched in portal tracts and respond to biliary epithelial cells presenting bacterial ligands during liver inflammation
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MAIT cells are activated during human viral infections.
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CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner.
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MAIT cells in the liver environment
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Biological functions of MAIT cells in tissues
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Innate‐like CD8+ T‐cells and NK cells: converging functions and phenotypes
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MAITs and their mates: "Innate-like" behaviors in conventional and unconventional T cells
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MR1-dependent activation of intrahepatic MAIT cells by bacterially exposed biliary epithelial cells and liver B cells
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MAIT cells are activated during human viral infections
od: Bonnie van Wilgenburg, i wsp.
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Bacteria exposed biliary epithelium and liver B cells activate intrahepatic mait cells in an MR1-dependent manner
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Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF-dependent mechanism
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MAIT cells protect against lung injury
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Wydane: (2024)

Activation and in vivo evolution of the MAIT cell transcriptome in mice and humans reveals tissue repair functionality
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Swimming Against the Current: MAIT Cell Function Is Preserved in the Peritoneum of Advanced Liver Disease Patients
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MAIT cells protect against sterile lung injury
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Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.
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MAIT cells play a role in liver tissue repair via growth factor secretion
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MAIT Cells in Barrier Tissues: Lessons from Immediate Neighbors
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MAIT cells and the microbiome
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Wydane: (2023-02-01)

MAIT cells protect against sterile lung injury
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Human MAIT cells respond to and suppress HIV-1
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Wydane: (2021)

Diverse Streptococcus pneumoniae strains drive a MAIT cell response through MR1-dependent and cytokine-driven pathways.
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Wydane: (2017)

MAIT cells and the microbiome
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Wydane: (2023)

Identification and phenotype of MAIT cells in cattle and their response to bacterial infections
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Wydane: (2021)

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality
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Wydane: (2019-09-01)